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Semi-structured interviews with a purposive sample of 28 practising GPs; sampled by antidepressant prescribing volume, practice size and deprivation level.A topic guide drawing on past literature was used with enough flexibility to allow additional themes to emerge. Constant comparison and disconfirmation were carried out across transcripts, with data collection being interspersed with analysis by three researchers.Potential participants showing interest were then contacted by CFJ to arrange interviews at their offices’.

These were then subcategorised as small (single handed GP), medium (2-3 GPs) and large (≥4 GPs) by the number of GPs contracted to individual practices, as recorded in April 2014 [Between August 2014 and December 2015, GPs matching the sampling frame were initially contacted by letter and followed up by telephone within 2 weeks by administrative staff.lack of safety concerns) and lack of proactive medication review (e.g.patients only present in crisis), all combine to further drive antidepressant prescribing growth over time. Antidepressants are only a single facet of depression treatment.DDDs are units of measurement defined by the World Health Organization as ‘the assumed average maintenance dose per day for a drug used for its main indication in adults’.DDDs do not necessarily reflect the recommended or prescribed daily dose but allow a convenient method to compare prescribing volumes between organisations [ One-to-one, face-to-face, semi-structured interviews were carried out by one researcher, a prescribing support pharmacist (CFJ), at the GP’s office.

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