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The bacteria have developed resistance against many of the drugs available in the market.

Halgamuge "Self-Organizing Hierarchical Particle Swarm Optimizer With Time Varying Acceleration Coefficients" IEEE Trans. A well organized research comprising of analogue based drug design and molecular dynamics plays a major role in obtaining the lead molecules. Black PN, Di Russo CC, Metzger AK, Heimert TL (1992): Cloning, sequencing, and expression of the fad D gene of Escherichia coli encoding Acyl coenzyme A Synthetase.

Eberhart "Fuzzy Adaptive Particle Swarm Optimization" Evolutionary computation, 2001 proceeding of the 2001 congres on vol.1 page no.

Gaing, "Particle Swarm Optimization to solving the economic dispatch considering generator constraints," IEEE Trans.

Key words: docking, homology modeling, leprosy, M.leprae, molecular, molecular dynamics, ramachandran plot.

Therefore identification of the novel drug target and potent drug can be helpful in better prevention of the disease. Alter et.al, (2008) Leprosy as a genetic model for susceptibility to common infectious disease, Hum Genet 2. (1999)Health Policy and Planning; 14(2): 89-102, Oxford University Press.

The hydraulic resisting forces, piston speed and mass flow rates are computed. Chenoweth, Aircraft flight control actuation system design vol.

Adhinarayanan, Maheswarapu Sydulu "Particle Swarm Optimisation for Economic Dispatch with Cubic Fuel Cost Function", TENCON 2006, IEEE region conference. Acyl Co A Synthetase is an enzyme that participates in fatty acid biosynthesis. The performance of proposed cellular genetic algorithms is examined under three dynamic optimization problems with different change severities.

Most of the genes are involved in biosynthetic and metabolic pathways, so the product of these genes can be aimed for the novel drug target. Transmembrane movement of exogenous long-chain fatty acids: proteins, enzymes, and vectorial esterification. Moreover, in the second proposed rule, the competition scheme of the best individuals within the neighborhoods of one individual is also introduced.

Proceedings of the 2005 IEEE International Conference on Robotics and Automation Barcelona, Spain, April 2005. Dongwoon Choi, Woonghee Shon and Ho-Gil Lee "Design of 5 D. F Robot Hand with an artificial skin For An Android Robot" Department of Applied Robot Technology, Korea Institute of Industrial Technology Republic of Korea.

Innas, "Cylinder Control with the floating cup hydraulic transformer," Proc. Key words: robot hand, Robotics, Robot Finger, Finger joints, FEA modeling. Ikuo Yamano, Takashi Maeno " Five Fingered Robotic hand Using Ultrasonic Motors and Elastic Elements" Department of Mechanical Engineering, Kieo University Hiyoshi Yokohama 223-8522, Japan. Zhe Xu, Emanual Todorov, Brian Dellon and Yoky Matsuoka " Design and Analysis of an artificial finger Joint for anthromorphic Robotic hands" Department of computer science & Engineering, University of Washington, WA 98195 USA. Gabriel Gómez , Alejandro Hernandez and Peter Eggenberger Hotz "An adaptive neural controller for a tendon Driven Robotic Hand" Artificial Intelligence Laboratory Department of Informatics, University of Zurich, Switzerland.




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