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Each lung is composed of smooth, shiny lobes; the right lung has three lobes and the left has two. Fresh oxygen moves into the capillaries, and carbon dioxide passes from the capillaries into the bloodstream, where it is carried out of the body through the lungs.Blood vessels carry the oxygen-rich blood to the heart, where it is pumped throughout the body. However, pneumonia can also be caused by viruses, fungi, and other agents. Pleura - the lining of the lungs Visceral pleura – the layer of the pleura lining the lungs which cannot be separated from the lungs.There are more than 80 capsular serotypes (each reacting with specific typing serum), but most cases of pneumococcal pneumonia are caused by 23 serotypes.

Capsular polysaccharide elicits primarily a B cell (i.e. Capsular antibody opsonizes the organism, facilitates phagocytosis, and promotes resistance to the disease.

Healthy people can usually fight off pneumonia infections.

However, people who are sick, including those who are recovering from the flu (influenza) or an upper respiratory illness, have weakened immune systems that make it easier for bacteria to grow in their lungs.

Carried in the nasopharynx of 40-70% of humans without symptoms.

(Highest carriage by children – see Table 13.1 in text) b. Complications: (1) Pleural effusions – serous fluid in the pleural space (2) Empyema – pneumococci enter the pleural space (3) Bacteremia (15-50% of patients) (4) Meningitis -from the bloodstream, bacteria can cross the blood- brain barrier and infect the meninges.

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